Impact of tumor markers in diagnosis of patients with hepatocellular carcinoma (HCC) and their clinicopathologic correlation: an interim analysis
D Bettinger, M Schultheiß, J Bürk, E Panther, E Knüppel, R Küper, R Thimme, HE Blum, HC Spangenberg · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and its incidence is rising. Diagnosis is mainly based on ultrasound performance whereas AFP measurement is not recommended according the current AASLD guidelines. The aim of this study is to determine the usefulness of α –fetoprotein (AFP), AFP-L3% and des-γ-carboxyprothrombin (DCP) in diagnosis of HCC and their correlation to clinicopathologic parameters. Methods: Both serum samples of 75 patients with confirmed HCC according the AASLD guidelines receiving transarterial chemoembolisation and of 175 patients with liver cirrhosi…