Effects of transcutaneous spinal direct current stimulation in patients with idiopathic Restless Legs Syndrome (iRLS)

Introduction: Several studies have indicated that patients with iRSL may have an increased spinal cord exictability. Thoracic transcutaneous spinal cord stimulation (tsDCS) is a noninvasive tool for spinal cord neuromodulation. This study aimed to establish a new safe method to modulate spinal excitability in iRLS patients and alleviate symptom severity. Methods: This double-blind, crossover study evaluated the soleus Hmax/Mmax ratio, the soleus H reflex recovery curves, and symptom severity before, at current offset and 30 min after sham, andodal and cathodal transcutaneous spinal direct current stimulation (2.…