Tremor clusters in the VIM associated with Essential tremor and Parkinson’s disease
DJ Pedrosa, C Reck, M Maarouf, L Wojtecki, A Pauls, V Sturm, A Schnitzler, GR Fink, L Timmermann · Klinische Neurophysiologie · 2012 · Heft 03
Bibliografische Angaben
Zusammenfassung
Objective: To investigate neurophysiological changes in the ventral intermediate nucleus (VIM) in patients suffering from Essential Tremor (ET) and Parkinson's disease (PD). Methods: We investigated the electrophysiological changes in 11 ET and 4 PD patients by simultaneously recording local field potentials (LFPs) in the VIM (at different recording depths) and surface electromyographic signals (EMGs) from the extensor and flexor muscles of the contralateral forearm. Subsequently coherence between both signals was computed for single and double tremor frequency and the distribution within the different heights i…