Late effects after Chemotherapy versus Allogeneic Stem Cell Transplantation in Childhood Relapsed Acute Lymphoblastic Leukemia – A report from the ALL-REZ BFM Study Group
N Biesold, F Meyr, G Henze, M Ranke, JD Beck, W Ebell, T Klingebiel, C Peters, A von Stackelberg · Klinische Pädiatrie · 2012 · Heft 03
Bibliografische Angaben
Zusammenfassung
To assess late effects in patients with relapsed ALL after chemotherapy versus allogeneic stem cell transplantation (SCT) we initiated an analysis on children diagnosed with acute lymphoblastic leukemia (ALL) in 2nd complete continuous remission (CCR) for more than 2 years previously treated according to ALL REZ BFM trials 1983–1996. Patients were selected by a matched cohort design with match parameters considered most relevant for the development of specific late effects. A standardized questionnaire for retrospective evaluation of late effects was sent to 57 clinical centers in Germany, Austria and Switzerlan…
