NAFLD and associated changes in serum Pro-hepcidin, Iron, Ferritin R levels and total iron binding capacity in weaning Rattus norvegicus

Background/aim: Excessive iron deposition in body is hazardous to life. Among many reasons of iron overload, NAFLD is under surveillance now a day. The purpose of the present experimental study was to analyse the impact of fat induced NAFLD and fat reducing agents on iron metabolism. Methodology: Four groups (n=10) of weaning Rattus norvegicus (30g) were designated as Control (Con), I, II, and III. Con group was fed on normal rat chow, I, II and III were provided with diet ''A'' (33% carbohydrate + 33% fat + 34% rat chow). The diets of group II and III were provided with 5% Nigella sativa and 5% Plantago ovata a…