Clinical value of microbiological analysis of peri-pancreatic fluid collection and its impact on antibiotic management: A prospective multi-center study

Aims: Secondary infection of peri-pancreatic fluid collection (PPFC) that often accompanies pancreatic disorders is potentially life-threatening as it may lead to intra-abdominal abscess or sepsis. Microbiological analysis of aspirates from PPFC during endoscopic ultrasound (EUS) diagnosis/therapy to optimize the antibiotic treatment is rarely performed. Aim of this study was to evaluate the role of routine aspirate from PPFC collection for microbiological analysis during EUS in the antibiotic management and to compare aspirates from PPFC with the corresponding concomitant blood culture. Methods: In this prospec…