Differentiation of high and low grade tumours in paediatric patients by using apparent diffusion coefficients

Objektive: This study was performed to confirm the hypothesis that preoperative apparent diffusion coefficient (ADC) can be used to distinguish between „low grade“ and „high grade“ tumours in paediatric patients. Material and methods: Thirty-two paediatric brain tumours were evaluated. Twenty-one children with low grade brain tumours (14 WHO I astrocytomas, 4 WHO II astrocytomas, 2 craniopharyngeomas and 1 ganglioglioma) and 11 children with high grade brain tumours (5 medulloblastomas, 1 ependymoma, 1 PNET, 1 malignant rhabdoid tumor, 1 malignant germ cell tumor, 1 WHO IV astrocytoma, 1 rhabdomyosarcoma metasta…