White matter injury in Premature Infants and Its Evaluation

Cerebral white matter injury is one of the most common neurological diseases in premature infants. Necrosis and decreased volume of white matter represent the characteristic changes of white matter injury. It can result in long-term neurological sequelas, including cerebral palsy, audio-visual abnormality, cognition dysfunction and epilepsy. We must pay more attention to the white matter injury in preterm infants. The primary pathogenesis of white matter injury is tissue ischemia. The cerebral blood vessels are immature in premature infants. The pressure-passive mechanisms of cerebral circulation is existing. Pr…