Time-of-Flight Angiography at 7 Tesla visualizes Tumor Vessels in Patients with Newly Diagnosed Glioblastoma

Ziele: Malignant glioma are among the most vascularized of all human tumors. Due to small vessel size, MR imaging of the tumor vasculature in glioma is challenging. Here we analyzed if time of flight (TOF) angiography at 7 Tesla can visualize tumor vessels in patients with newly diagnosed glioblastoma. Methode: Ten patients with newly diagnosed glioblastoma were examined on a whole-body 7 T MR system. TOF MRA data were acquired with imaging parameters: flip angle = 19°, TR = 15 ms, TE = 4.8 ms, FOV = 154×210 mm2. Two readers graded the appearance of tumor vessels via consensus reading as grade 0: no tumor vessel…