Serum levels of growth arrest specific protein 6 are increased in preeclampsia
W Schaarschmidt, J Richter, K Kley, S Kralisch, A Jank, T Ebert, U Lössner, B Jessnitzer, J Kratzsch, M Blüher, S Michael, M Fasshauer, H Stepan · Geburtshilfe und Frauenheilkunde · 2013 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background: Preeclampsia (PE) contributes to maternal and fetal morbidity and mortality worldwide. Moreover, it is associated with an increased future metabolic and cardiovascular risk for mother and newborn. Recently, growth arrest specific protein (Gas) 6 has been introduced as a novel metabolic risk factor with anti-angiogenic, pro-atherogenic, and pro-adipogenic properties. Methods: In the current study, we investigated serum concentrations of Gas6 in patients with PE (n = 51) as compared to healthy, age-matched controls (n = 51) during and 6 months after pregnancy. Furthermore, association of Gas6 with mark…
