Endoscopic ultrasound in staging esophageal cancer after neoadjuvant chemotherapy – results of a multicenter cohort analysis

Purpose: Endoscopic ultrasound (EUS) is considered a gold standard in the initial staging of esophageal cancer. There is an ongoing debate whether EUS is useful for tumor staging after neoadjuvant chemotherapy (NAC). Material and methods: Ninety-five patients with esophageal cancer were retrospectively analyzed. In 45 patients EUS was performed prior to and after NAC while 50 patients had no induction therapy. Histological correlation through surgery was available. uT/uN classifications were compared to pT/pN stages. Statistical analysis included calculation of sensitivity, specificity and accuracy rates. Agreem…