Prenatal diagnosis of anomalies of the corpus callosum over a 13 years period

Purpose: The clinical use of detailed fetal neurosonography has increased during recent years. Therefore more subtle and rare cerebral malformations such as corpus callosum anomalies are detected. This retrospective study explored the spectrum and frequency of different forms of corpus callosum anomalies (CCA) in a level III centre setting. Material and methods: Between 1999 and 2012 about 40.000 detailed second and third trimester scans were performed. Among them 140 (0.35%) cases of CCA were diagnosed. Differentiation between complete and partial agenesis, hypoplastic CC and isolated and non-isolated forms was…