CareLit Fachartikel

Toxic Effects of Multiwall Carbon Nanotubes (MWCNT) in vivo and in vitro

A Hackbarth, D Schaudien, B Bellmann, H Ernst, C Ziemann, A Leonhardt, U Heinrich, S Rittinghausen · Pneumologie · 2013 · Heft 12

Dokument
822806
CareLit-ID
Jahr
2013
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
A Hackbarth, D Schaudien, B Bellmann, H Ernst, C Ziemann, A Leonhardt, U Heinrich, S Rittinghausen
Ausgabe
Heft 12 / 2013
Seiten
–
Erschienen: 2013-12-09 00:00:00
ISSN
0934-8387
DOI
10.1055/s-0033-1357050

Zusammenfassung

MWCNTs have excellent technological features and there is rapid growth in MWCNT development and production. However, concerns of asbestos-like toxic effects of certain MWCNTs exist due to their length and fiber-like shape. Therefore, potential adverse biological effects of MWCNTs are investigated in vivo (rat) and in vitro (human peritoneal mesothelial LP9/TERT-1 cells) in a project funded by the BMBF (contract No. 03X0109A). Custom made MWCNTs with different lengths and diameters were synthesized and suspended in artificial lung-like or culture medium by ultrasonic treatment. For both the in vivo and the in vit…

Schlagworte

Pneumologie