Screening of pregnant women to reduce fetal and neonatal alloimmune thrombocytopenia (FNAIT)
M Killie, H Tiller, O Flodmark, B Skogen, A Husebekk, J Kjeldsen-Kragh · Zeitschrift für Geburtshilfe und Neonatologie · 2013 · Heft 11
Bibliografische Angaben
Zusammenfassung
Aim: Present updated results from the large prospective screening study for neonatal alloimmune thrombocytopenia that was published in Blood in 2007.1 Method: In 100,448 pregnancies human platelet antigen (HPA)-1 typing was performed and HPA 1bb women with anti-HPA-1a antibodies were followed-up during pregnancy and delivered by caesarean section (CS) in week 36 – 38. Compatible platelets were available for immediate transfusion to the newborn. The results were compared with historical controls. Result: The results from our previously published study1 showed that there was a significant reduction of intracranial…
