Three-dimensional Chemical Exchange Saturation Transfer (CEST) Imaging at 7 Tesla in Glioblastoma Patients
A Radbruch, D Paech, J Windschuh, JE Meissner, HP Schlemmer, P Bachert, M Ladd, M Bendszus · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2014 · Heft 04
Bibliografische Angaben
Zusammenfassung
Zielsetzung: To evaluate the additional information provided by three dimensional chemical exchange saturation transfer (CEST) magnetic resonance (MR) imaging in newly diagnosed patients with glioblastoma multiforme (GBM) at 7 Tesla (7T) and its diagnostic benefits, compared to standard MR imaging. Material und Methodik: 11 Patients with histologically proven glioblastoma were enrolled in this prospective study with the approval of the local ethics committee after written informed consent was obtained. CEST contrast was obtained with a modified three-dimensional gradient-echo sequence (˜10 min 30 s) and a 24-cha…