Vulvo-vaginal intestinal/enteric heterotopia – report of two cases

Background: The occurrence of ectopic intestinal/enteric type epithelium at the vulva is a rare entity sometimes mimicking intraepithelial neoplasia or malignant disease. Methods: Here we report two cases. Results: The first consisted of an 82-year old woman with a long standing (10 years) white papillary lesion with some reddish areas at her left labium, extending into the vaginal introitus. The second case occurred in an 30-year old women at the vaginal introitus. Biopsies represented colonic-type glandular epithelium with positive immunostaining against CDX-2, p53, CK 7 and CEA, whereas staining against estro…