CareLit Fachartikel

Individualisation of radiochemotherapy (RTCT) for locally advanced non-small cell lung cancer (NSCLC)

A Tufman, A Borgmeier, C Belka, K Ulm, F Tian, M Flentje, P Schnabel, T Goldmann, RM Huber · Pneumologie · 2014 · Heft 06

Dokument
823866
CareLit-ID
Jahr
2014
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
A Tufman, A Borgmeier, C Belka, K Ulm, F Tian, M Flentje, P Schnabel, T Goldmann, RM Huber
Ausgabe
Heft 06 / 2014
Seiten
–
Erschienen: 2014-06-10 00:00:00
ISSN
0934-8387
DOI
10.1055/s-0034-1376830

Zusammenfassung

Background: Individualised therapy has not yet found its place in the treatment of stage III NSCLC. Although RTCT can be curative, many tumours progress despite multimodal treatment. The CTRT 99/97 Bronchial Carcinoma Therapy (BROCAT) study investigated radiotherapy (RT) vs. RTCT after induction chemotherapy. The German Intergroup Lung Trial (GILT) investigated consolidation CT following simultaneous RTCT. Here we present clinical and translational predictors of outcome in these two large randomised trials. Methods: We analysed histology subgroups within BROCAT, comparing adenocarcinoma, squamous cell and large…

Schlagworte

Pneumologie