A Case with Pulmonary Alveolar Proteinosis and Sarcoidosis

Introduction: Autoimmune pulmonary alveolar proteinosis (PAP) is a rare lung disease caused by autoantibodies against GM-CSF. Sarcoidosis is a systemic granulomatosis mostly involving the lung. The pathogenesis of both immune mediated disorders remains unclear. Case Report: 55 years old female patient presented with dyspnoea and cough in the hospital in Stuttgart. High-resolution computed tomography (HRCT) demonstrated ground glass opacities with crazy paving pattern, which was compatible with pulmonary alveolar proteinosis (PAP). Bronchoalveolar lavage (BAL) and tranbronchial lung biopsy (TBB) were typical for…