Gastric bypass improves subclinical nephropathy in non-severely obese patients (BMI < 35 kg/m2) with type 2 diabetes mellitus
AT Billeter, S Kopf, B Israel, T Schulte, P Knefeli, MW Büchler, PP Nawroth, BP Müller · Diabetologie und Stoffwechsel · 2015 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Bariatric surgery results in high remission rates of type 2 diabetes mellitus (T2DM) in obese patients. We have previously shown that Roux-en-Y gastric bypass (RYGB) improves diabetic neuropathy, likely due to a reduction in nitrosative stress. The purpose of this study was to investigate whether RYGB is also able to improve diabetic nephropathy. Methods: Twenty consecutive patients with a body mass index (BMI) between 25 – 35 kg/m2 and a poorly controlled, insulin-dependent T2DM were enrolled. All patients were treated with a standardized RYGB. Changes in serum creatinin levels, urinary albumin ex…
