CareLit Fachartikel

SPARC expression in primary metastatic breast cancer

J Barinoff, C Brandi, M Thill, C Heinrichs, J Mensah, W Weikel, A Fisseler-Eckhoff, H Sinn, A Meyer, A Traut, A Schneeweiss · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2015 · Heft 05

Dokument
825085
CareLit-ID
Jahr
2015
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Senologie - Zeitschrift für Mammadiagnostik und -therapie
Autor:innen
J Barinoff, C Brandi, M Thill, C Heinrichs, J Mensah, W Weikel, A Fisseler-Eckhoff, H Sinn, A Meyer, A Traut, A Schneeweiss
Ausgabe
Heft 05 / 2015
Seiten
–
Erschienen: 2015-05-22 00:00:00
ISSN
1611-6453
DOI
10.1055/s-0035-1550450

Zusammenfassung

Einleitung/Zielsetzung: To evaluate the prognostic value of the expression of secreted protein acidic and rich in cysteine (SPARC) in primary metastatic breast cancer (PMBC). Material & Methoden: Fifty-two patients with PMBC diagnosed between 2005 and 2012 at x German centers were retrospectively analyzed for expression of SPARC in tumor cells using an immunoreactive score (IRS) integrating staining intensity and percentage of positive cells (IRS 0 – 12), and in stroma based on immunohistochemical (IHC) staining intensity only (IHC 0 – 3+). Association between SPARC expression, tumor characteristics and progress…

Schlagworte

Tumor Breast Association Cysteine Senologie - Zeitschrift für Mammadiagnostik und -therapie