Efficacy of Peginterferon plus Ribavirin in patients receiving Opioid substitution therapy – final results of the Austrian Peghope-study

Background: Patients included in an official opioid substitution program represent an important subgroup of patients with chronic hepatitis C. Treatment of these patients with peginterferon plus ribavirin has yielded conflicting results. However, interferon-based regimens are still deemed standard of care in many parts of the world due to high costs of new direct acting antivirals. Patients and Methods: This prospective, multicenter, observational, non-interventional trial (clinicaltrials.gov identifier, NCT01416610) included treatment-naïve patients with chronic hepatitis C undergoing opioid maintenance therapy…