Serum lipid parameters in patients with chronic hepatitis C during IFN-free treatment: effect of HCV genotype and cirrhosis
C Freissmuth, AF Stättermayer, K Kozbial, S Beinhardt, M Eder, P Munda, M Trauner, P Ferenci, H Hofer · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background & Aims: Hepatitis C virus (HCV) genotype-(GT)-3 inhibits the microsomal triglyceride transfer protein (MTP) leading to hepatic steatosis and alterations in lipid metabolism, which were shown to be reversible after successful HCV eradication. Aim of this study was to investigate the effect of IFN-free antiviral therapy on serum lipid parameters in patients with and without cirrhosis. Patients & Methods: Total serum cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL) and serum triglycerides were analyzed at baseline and during antiviral therapy in 105 chronic hepatitis C patients…
