25-hydroxyvitamin D deficiency is associated with decreased light exposure as quantified with actigraphy but not with dietary sources in patients with chronic liver diseases

Background: Patients with chronic liver diseases (CLD) commonly exhibit vitamin D deficiency due to a combination of exogenous and endogenous factors (Hepatology 2012;56:1883). It remains unknown to which extent CLD contribute to vitamin D deficiency. The aim of this study was to assess for possible associations of exogenous factors (sunlight exposure and dietary intake) with serum vitamin D levels in CLD patients. Methods: Serum 25-hydroxyvitamin D concentrations were measured with chemiluminescence immunoassay in patients with CLD. We quantified light exposure using the accelerometer-based physical activity mo…