Small dense LDL cholesterol is a cardiovascular risk factor in several chronic inflammatory diseases
K Paulsen, D Schulte, K Türck, S Freitag-Wolf, I Hagen, R Zeuner, JO Schröder, W Lieb, A Franke, S Nikolaus, U Mrowietz, S Gerdes, S Schreiber, M Laudes · Diabetologie und Stoffwechsel · 2016 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Subjects with Chronic inflammatory diseases (CID) exhibit a profound increase of cardiovascular risk (CVR) resulting in reduced life expectancy. At the same time LDL-cholesterol serum levels seem to be low in these patients suggesting a special type of “rheumatic dyslipidemia”. Methods: In our mono-centre, longitudinal, observational study small dense LDL-cholesterol (sdLDL) was measured in n = 143 subjects with CID (Rheumatoid Arthritis n = 59, Inflammatory Bowel Disease n = 35, Ankylosing Spondylitis n = 25, Psoriasis n = 22) at baseline, 6 and 26 weeks after initiation of different anti-cytokine…