A New Prognostic Score for Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma – An Update
I Opitz, M Friess, O Lauk, T Frauenfelder, TDL Ngyuyen, I Inci, S Hillinger, D Schneiter, B Seifert, R Stahel, W Weder · Zentralblatt für Chirurgie · 2016 · Heft 09
Bibliografische Angaben
Zusammenfassung
Hintergrund: We developed a Multimodality Prognostic Score (MMPS) in our patient cohort receiving induction chemotherapy followed by extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D) to facilitate the decision for surgery after induction chemotherapy. Material und Methode: A 4 variable MMPS was developed including pre-chemotherapy tumor volume (> 500 ml), progressive disease (PD) after induction chemotherapy (according to modified RECIST criteria), pre-chemotherapy CRP (> 30 mg/ml) and non-epithelioid histological subtype. Overall survival (OS) was calculated from the first cycle of induction c…
