CareLit Fachartikel
Impaired decision making in hepatic encephalopathy relates to attenuated BOLD-signal in the right inferior parietal cortex
G Kircheis, O Zafiris, HA Rood, F Boers, K Zilles, D Häussinger · Zeitschrift für Gastroenterologie · 2004 · Heft 02
Dokument
850222
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Jahr
2004
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Zusammenfassung
Aim: Impaired decision-making is observed in Hepatic Encephalopathy (HE). The underlying brain mechanisms of this metabolically induced behavioural alteration are not known. The aim of this functional MRI (fMRI) study was to identify brain regions showing differences in BOLD-response between controls and cirrhotic patients without manifest HE. Methods: 10 healthy controls, 9 patients with non-manifest HE (5 HE 0; 4 minimal [mHE]) were studied. For each volunteer 221 fMRI images (26 behavioural trials) were acquired (whole brain coverage) with a Siemens Vision 1.5T scanner. During an experimental session intrafov…
Schlagworte
BOLD-signal
Critical Flicker Frequency
Hepatic Encephalopathy
clinical study
functional MRI
Zeitschrift für Gastroenterologie
