Plasma carnitine ester profile in Crohn's disease
K Horváth, B Gasztonyi, J Bene, K Komlósi, V Havasi, G Talián, V Vélin, S Varjú, M Juhász, Z Tulassay, I Juricskay, G Mózsik, B Hunyady, B Melegh · Zeitschrift für Gastroenterologie · 2004 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Very recent data show that the human OCTN1 and OCTN2 carnitine (C) transporter orthologs likely map to the IBD5 locus at 5q31, which has been suggested to confer susceptibility to Crohn's disease (CD). Therefore, a link between a pathogenic role of C and the CD can exist. The circulating C ester profile has not been investigated in CD. Aim: We determined the plasma C profile in adult patients with CD and compared with healthy control subjects. Patients and methods: The circulating C profile were detected by ESI triple quadrupol tandem mass spectrometry in 41 patients with CD and in 31 healthy age and…
