Release of brain-type and heart-type fatty acid-binding proteins in serum after acute ischaemic stroke

Background and Purpose: The study aimed at an analysis of the release of Brain-type and Heart-type Fatty Acid-Binding Proteins (B-FABP and H-FABP) in acute ischemic stroke and their potential value as neurobiochemical markers of brain damage. Methods: We investigated 42 consecutive patients admitted within 6 hours (median 3 hours) after stroke onset. Serial venous blood samples were taken hourly between 1 to 6 hours, and at 12, 18, 24, 48, 72, 96, and 120 hours after stroke onset. In all patients lesion topography was analyzed and infarct volume was calculated. The neurological deficit was quantified by the Nati…