Magnetic Fluid Hyperthemia (MFH) as an adjuvant therapy in the treatment of malignant gliomas

Introduction: The prognosis of glioblastoma (GB) remains poor despite the better neuro-imaging modalities and neurosurgical techniques. The survival of patients (PTS) depends on local tumour control, which is not guaranteed by the actual standard therapy. Magnetic fluid hyperthermia (MFH) in combination with external irradiation (RT) is a worldwide new method, which heats up selectively tumour tissue coupling a magnetic field to the applicated magnetic fluid (MF). Patients and methods: In a phase I study with 15 PTS the applicability and tolerance of MFH combined with RT was evaluated. We present our preliminary…