Depression und Parkinson-Krankheit
Matthias R. Lemke · psychoneuro · 2004 · Heft 08 · S. 426-433
Bibliografische Angaben
Zusammenfassung
Zusammenfassung Depression affects approximately 45 % of all patients with Parkinson's disease, reduces quality of live independent of motor symptoms and seems to be underrated and undertreated. Depression may manifest as a first symptom of Parkinson's disease many years before motor deficits. Serotonergic, noradrenergic and dopaminergic mechanisms play key roles in the etiology of depression in Parkinson's disease. Tricyclic and newer, selective antidepressants including serotonin and noradrenaline reuptake inhibitors (SSRI, SNRI) in combination with psychoeducation are effective in treating depression in Parki…