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Impact of different lipid emulsions on acute lung injury in a murine model

MH Bi, BE Wang, J Ott, A Mohr, MB Schäfer, W Seeger, K Mayer · Pneumologie · 2005 · Heft 03

Dokument
852165
CareLit-ID
Jahr
2005
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
MH Bi, BE Wang, J Ott, A Mohr, MB Schäfer, W Seeger, K Mayer
Ausgabe
Heft 03 / 2005
Seiten
–
Erschienen: 2005-03-03 00:00:00
ISSN
0934-8387
DOI
10.1055/s-2005-864291

Zusammenfassung

Background: Acute lung injury (ALI) is the most common presentation of sepsis-associated multiple organ failure, characterized by increased alveolar cytokines and inflammatory cell infiltration. Arachidonic acid gives rise to the eicosanoid family of inflammatory mediators and through these regulates activities of inflammatory cells and production of cytokines. Lipid emulsions are used as supplement of parenteral nutrition in intensive care units. Clinoleic®, a new lipid emulsion, was developed to reduce arachidonic acid available, which might reduce inflammatory responses. We investigated impact of two differen…

Schlagworte

Arachidonic Acid Cytokines Acute Lung Injury After Bronchoalveolar Lavage Fluid Bronchoalveolar Lavage Chromatography Cytokine Sepsis Pneumologie