Continuous Arterial Spin Labeling (CASL) in clinical practice at 3.0 T – Results on Reliability and Quantification
C Manka, F Träber, W Block, L Scheef, J Gieseke, CK Kuhl, HH Schild · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2005 · Heft 04
Bibliografische Angaben
Zusammenfassung
Purpose: Continuous Arterial spin labeling (CASL) is a know alternative to DSC, where the T1 relaxation of magnetized “labeled“ protons are used as a freely diffusible intrinsic contrast medium. The positive aspect of this method is that the absolute cerebral blood flow is to be quantified Due to its dependence on the T1 relaxation time of the blood and the SNR, the acquisition was highly time consuming und the brain coverage limited to a few slices at field strengths up to 1.5 Tesla. These boundaries restricted the common use of CASL in clinical diagnostics and should be improved by using clinical high field MR…
