Automated histological classification of colon biopsy samples using image analysis on digital slides

Aims: Digital slides and virtual microscopy was shown to be alternative techniques for routine gastroenterological biopsy specimen analysis. Moreover automated, quantitative, reproducible classification of gastric slides into major histological diagnostic groups has been achieved by image analysis techniques. Aims: Our aim was to adopt our gastric experiences to the colon cases detecting cell nucleus, glands, and surface epithelium; and classify the samples to different disease classes using statistical data. Methods: Altogether 69 pieces of routine chronic colon well oriented mucosal biopsy specimen were select…