CareLit Fachartikel

Expression and interaction of proteinase-activated receptor-2 on rat myometrium

N Freerksen, Y Vedernikov, G Saade, G Gebauer, C Sohn, RE Garfield, H Maul · Zentralblatt für Gynäkologie · 2005 · Heft 05

Dokument
852507
CareLit-ID
Jahr
2005
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zentralblatt für Gynäkologie
Autor:innen
N Freerksen, Y Vedernikov, G Saade, G Gebauer, C Sohn, RE Garfield, H Maul
Ausgabe
Heft 05 / 2005
Seiten
–
Erschienen: 2005-05-25 00:00:00
ISSN
0044-4197

Zusammenfassung

Objective: Regulation of uterine contractility at all stages in gestation is extremely important. The function of uterine activity depends on spontaneous contractions of the myometrial smooth muscle cells, triggered by incoming action potentials. Stimulation of proteinase-activated receptor-2 (PAR-2) has been shown to induce myometrial activity. This study wanted to 1) determine the expression of PAR-2 on rat myometrium at different times of the gestational cycle and 2) investigate how PAR-2 gestation-dependently interacts with a variety of uterine receptors known to modulate myometrial activity. Study design: E…

Schlagworte

After ANOVA Action Potentials Acetylcholine Atropine Krebs Zentralblatt für Gynäkologie