CareLit Fachartikel
Nigral dopamine release – preclinical studies of its implication in motor functions
F Bergquist, D Andersson, H Nissbrandt · Aktuelle Neurologie · 2005 · Heft 09
Dokument
852646
CareLit-ID
Jahr
2005
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Zusammenfassung
Since the discovery of nigral somatodendritic dopamine release thirty years ago, the physiological function and relevance of this phenomenon have been debated. Autoinhibitory functions, as well as modulation of GABA-ergic, glutamatergic and serotonergic transmission in substantia nigra (SN) pars reticulata have been described, but the physiological importance of these mechanism for motor functions has been difficult to determine. We have previously described a method for combining microdialysis dopamine measurements in SN and the striatum of awake rats with reverse dialysis of drugs during simultaneous motor per…
Schlagworte
Dialysis
Movement Disorders
Basal Ganglia
Biochemistry
Movement
Aktuelle Neurologie
