AN MRI CONTRAST AGENT FOR ULTRASONIC IMAGING? A BACKSCATTERING SIMULATION
M Mienkina, C Hansen, G Schmitz · Ultraschall in der Medizin - European Journal of Ultrasound · 2005 · Heft 09
Bibliografische Angaben
Zusammenfassung
Problemstellung: Superparamagnetic iron oxide (SPIO) nanoparticles coated by Carboxydextran (Ferucarbotran) are used as contrast agents for magnetic resonance imaging (MRI). These agents, like Resovist®, are used for the detection of focal liver lesions since they are only aggregated in Kupffer cells located in healthy liver tissue. Recently, it has been shown in vivo that these agents are detectable in liver sonography, too. We investigate their acoustical behaviour based on linear acoustic scattering theory for inhomogeneous media. Methoden: We derived an acoustic backscattering model using a spatial autocorre…