Curative endoscopic resection of early esophageal adenocarcinomas (Barrett’s cancer)

Background & Aims: In view of the increasing incidence of adenocarcinoma in Barrett’s esophagus and the mortality and high morbidity rates associated with surgical therapy for this condition, safe and effective, but less invasive, methods of treatment are needed. Methods: In a prospective single-center trial conducted between October 1996 and September 2003, 100 consecutive patients (mean age 62.1±10.9; range 31–86) with low-risk adenocarcinoma of the esophagus (macroscopic types I, IIa, IIb, and IIc; lesion diameter up to 20mm; mucosal lesion without invasion into lymph vessels and veins; and histological grade…