Chronic and excessive alcohol consumption is causing elevated adiponectin serum levels

In animal models hepatic injury is causing elevated serum adiponectin levels, and adiponectin is revealing antifibrotic and hepatoprotective effects. Adiponectin is a plasma protein produced by the adipose tissue and decreased serum adiponectin levels are found in obese patients. The aim of this study was to analyze the effect of (chronic) excessive alcohol consumption on adiponectin expression and serum levels in vivo and in vitro. Patients and Methods: Serum specimens were collected from a) 75 heavy drinkers (>=80g/day; >5 years) without clinical or sonomorphological indications for advanced liver damage recru…