CareLit Fachartikel
Heat Shock proteins: come to rescue during acute phase response (APR).
N Sheikh., K Tron, G Ramadori · Zeitschrift für Gastroenterologie · 2006 · Heft 01
Dokument
854319
CareLit-ID
Jahr
2006
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Zusammenfassung
The heat shock proteins (Hsps) are a group of proteins that were originally identified on the basis of their increased synthesisin cells exposed to elevated temperatures but these proteins are also induced by other stimuli such as growth factors, inflammation and infection. Hsp–32 [heme oxygenase–1(HO–1)] is the inducible isoform of an enzyme family responsible for heme catabolism in mammals. HO–1 is the microsomal enzyme that catalyses the initial reaction in heme catabolism yielding equimolar amounts of biliverdin, carbon monoxide (CO) and free divalent iron. CO involve the increased expression of the 70-kDain…
Schlagworte
Heat shok proteins
acute phase response
heat shock protein 70.
heme oxygenase 1
turpentine oil
Zeitschrift für Gastroenterologie
