High opiate receptor binding potential in the human lateral pain system: A (FEDPN)PET study
U Baumgärtner, HG Buchholz, A Bellosevich, W Magerl, T Siessmeier, S Höhnemann, HJ Wester, F Rösch, P Stoeter, P Bartenstein, RD Treede, M Schreckenberger · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
To determine how opiate receptor distribution is co-localized with the distribution of nociceptive areas in the human brain, eleven male healthy volunteers underwent one PET scan with the subtype-nonselective opioidergic radioligand [18F]fluoroethyl-diprenorphine under resting conditions. The binding potential (BP), a parameter for the regional cerebral opioid receptor availability, was computed using the occipital cortex as reference region. The following regions of interest (ROIs) were defined on individual MR images: thalamus, sensory motor strip (SI/MI area), frontal operculum, parietal operculum, anterior i…
