Altered cortical activation of patients with blepharospasm during repetitive forearm contraction: an fMRI study
M Obermann, Î Yaldizli, A DeGreiff, ML Lachenmayer, F Tumszak, AR Buhl, J Vollmer-Haas, ER Gizewski, HC Diener, M Maschke · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Aims: Idiopathic blepharospasm is a common focal dystonia characterized by involuntary eyelid closure. Etiology appears to be multifactorial, including the influence of a genetic background and a possible environmental trigger. Genetics may play a role in reduced brain inhibition leading to increased brain plasticity. Objective: To determine whether cortical activation of patients with blepharospasm compared to healthy controls is altered during a repetitive forearm contraction task using fMRI. Methods: Eleven patients (mean age 52,45±10,82 SD; male 4 female 7) with blepharospasm were compared to seven (mean age…
