Enhanced plasma values of long-chain polyunsaturated fatty acids in patients with inflammatory bowel disease

Aim: Several studies demonstrated that long-chain polyunsaturated fatty acids (LCPUFA) may play an important role in the pathogenesis of inflammatory bowel disease, and dietary interventions with fish oils have been suggested. However, the available data on the LCPUFA status in patients with IBD are controversial. Patients and methods: Thirty patients with UC, 21 with CD and 24 controls (C) were investigated (age UC:40.8±12.1; CD:37.6±11.0; C:31.5±8.4 mean±SD). Fatty acid composition of plasma lipids was determined by high-resolution capillary gas-liquid chromatography. Results: In plasma phospholipids, signific…