Severe gastrointestinal manifestations of Henoch-Schönlein Purpura (HSP). Case report

Introduction: HSP is a systemic small vessel vasculitis characterized by vascular and/or mesangial IgA deposits, primarily affecting the vasculature of the skin, joints, kidneys and GI tract. Gastrointestinal findings of various severities occur in 50–85% of HSP patients. We report on a 70 year old woman who developed ileocoecal invagination and upper gastrointestinal haemorrhage as manifestations of HSP. Case history: The patient presented with two days' history of purpuric rash localized on the lower extremities. Based on the result of the skin biopsy, which showed leukocytoclastic vasculitis, IgA and C3 depos…