Fundic gland polyposis

Background: Fundic gland polyps (FGPs) are usually associated with familial adenomatous polyposis (FAP) or can be sporadic, but recently it is frequently observed among patients receiving long-term proton-pump inhibitor (PPI) therapy without H. pylori gastritis. Spontaneous regression of FGPs was reported with association of H. pylori acquisition or after PPI therapy stopped. Material: Among 2349 gastroscopies performed during the last year in the authors' gastroenterological ambulance there were 7 patients having fundic gland polyposis, 4 middle-aged women of them under long-term PPI therapy, the remaining 3 yo…