Selective bowel decontamination in acute necrotising pancreatitis

The high mortality (10–30%) of acute necrotising pancreatitis is bound up with (endogenous) infection of the necrotic tissues. Changing this connection is the aim of conservative treatment. Together with intensive care and enteral feeding, we used selective bowel decontamination (SBD) which can prevent endogenous infections by reducing the number of potentially pathogen microbes (aerobe bacteria, fungi) in the oropharynx and gastro-intestinal tract, saving anaerobe bacteria. We considered its influence on mortality, frequency of septic complications, number of invasive treatments needed and on hospitalization ti…