Myocardial meta-iodobenzylguanidin SPECT: a useful clinical tool?

Purpose: To evaluate the diagnostic usefulness of myocardial Metaiodbenzylguanidin SPECT (MIBG-SPECT) in patients with different parkinsonian syndromes (PS). Background: The cardiac uptake of MIBG-SPECT is reduced in idiopathic Parkinson's disease (IPD), Lewy Body dementia (LBD) and idiopathic REM sleep behaviour disorder (iRBD). It is normal in PS related to tauopathies and in other dementia disorders. Methods: The concordance of MIBG diagnosis (MD) and clinical diagnosis (CD) was evaluated in different clinical set-ups. CD was based on established guidelines and reassessed at the last follow up visit. MD was b…