Detection of disseminated tumor cells in patients with gynecological cancers
T Fehm, S Becker, C Bachmann, V Beck, K Sotlar, D Wallwiener, EF Solomayer · Geburtshilfe und Frauenheilkunde · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Abstract Aims: The presence of disseminated tumor cells (DTC) in breast cancer patients is associated with poor prognosis. However, there is limited data about the prevalence and prognostic impact of DTC in patients with gynecological tumors. The aim of this study was to evaluate the presence of DTC in the bone marrow (BM) of patients with gynecological cancers and to correlate their presence with established prognostic factors. Methods: In a prospective study bone marrow aspirates of 201 patients with primary ovarian (n=69), cervical (n=54) and endometrial cancer (n=78), undergoing surgery at the Department of…