Homocysteine in restless legs syndrome and Parkinson's disease
C.G. Bachmann, N. Guth, K. Helmschmied, V.W. Armstrong, W. Paulus, S. Happe · Aktuelle Neurologie · 2006 · Heft 09
Bibliografische Angaben
Zusammenfassung
Aims: Total plasma homocysteine (tHcy) is considered a risk factor for cardiovascular diseases. Elevated tHcy plasma concentrations are associated with vitamin B12, and folate deficiency or with renal failure. Previous studies revealed elevated tHcy plasma levels in patients with Parkinson's disease (PD), especially in PD patients with levodopa treatment. Objective: The aim of this study was to examine whether alterations in tHcy concentrations can be detected in patients with restless legs syndrome (RLS) in relation to levodopa treatment and to determine which role folate, vitamin B6 and B12 play in RLS. Method…