Histological verified focal myositis in familial Mediterranean fever

Objective: Familial Mediterranean Fever (FMF) is an autosomal recessive disease affecting predominantly people in Mediterranean and Middle Eastern populations due to mutations in the Mediterranean Fever gene (MEFV gene) on chromosome 16p13.3. It is characterized by recurrent attacks of fever, self-limited attacks of polyserositis and erysipelas-like skin lesions, accompanied by pain. The occurrence of myalgias is known, but the pathophysiology seems to be unclear. Methods: We report a 40 years old Turkish male suffering from genetically proven Familial Mediterranean Fever, treated with colchicine for 20 years, w…