Quantitative 3D-Micro-CT Imaging of the Human Lung Fibrosis
M Kampschulte, A Langheinrich, CR Schneider, C Dierkes, D Tscholl, C Schneider, C Zeiner, RM Bohle · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2009 · Heft 05
Bibliografische Angaben
Zusammenfassung
Ziele: To evaluate the feasibility of micro-CT imaging for analysis of the human lung fine structure. Methode: Using micro-computed tomography (micro-CT), 46 human lung samples derived from autopsy and resection from patients with severe lung fibrosis (n =9) or without lung disease (controls, N=3) were scanned. These samples were prepared and scanned non-contrast (native) and contrast enhanced (Osmium or HgCl2 or intravascular lead containing contrast agent (Microfil)). Soft tissue volume, total air space and vascular volume fraction were quantified. Results were complemented by histology. Differences on structu…
